A study of rural Appalachian counties from 2000 to 2017 found that severe, federally declared floods were followed by a 26% increase in opioid overdose death rates over the subsequent decade, compared to similar unaffected counties.
Researchers estimate roughly 1,368 of the 11,744 recorded opioid overdose deaths in the region during that period were connected to flood damage. The hardest-hit populations were people with no more than a high school education and residents of counties already classified as economically distressed.
Interviews with treatment and harm-reduction workers described flooded clinics, disrupted transportation, and displaced social networks as key drivers, alongside loss of access to naloxone and fentanyl test strips. Some providers improvised with ATVs and boats to keep services running.
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